Given a set of sequences, either weighted or unweighted, *k*pLogo performs statistical tests to find the most enriched and depleted short motif (*k*-mer) at each position, and visualizes the results using a new type of logo called *k*-mer logo, in which the most enriched/depleted *k*-mer at each position is plotted vertically and scaled by its statistical significance. In addition, *k*pLogo also outputs traditional logo plots for letter frequency, information content, and probability logo.

**Cite:**

Xuebing Wu and David Bartel (2017) *k*pLogo: positional *k*-mer analysis reveals hidden specificity in biological sequences, see preprint in bioRxiv.

Copyright (c) 2017 Xuebing Wu